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These results were validated using fluorescent miscroscopy and immunocytochemical staining ( Figure 4B ), which showed that CB-839 induced the accumulation of LC3 puncta in HG-3 and MEC-1 cells

Since deficits in glutathione have been linked to psychosis and schizophrenia, the team explained, chemical agents capable of restoring the balance in the brain between glutathione and glutamate may provide therapeutic benefit

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