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In fact, the only study that I could find involving humans was a very small retrospective study with just 16 participants

Deficiencies in vitamin B12 can manifest in numerous health issues, such as cognitive decline, memory loss, fatigue, and even neurological disorders like dementia

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Researchers have also investigated its contribution to experimental studies involving adipocyte biology, metabolic regulation, and intracellular energy pathways

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Alcohol and Vitamin B Deficiency Long-term heavy drinking can lead to a deficiency in vitamin B1 (thiamine) , increasing the risk of developing conditions like Wernicke-Korsakoff syndrome , a serious neurological disorder