Rarer side effects may emerge as more patients take these medicines in clinical practice, she said, "simply as a result of the much larger number of people treated than were included in the clinical development trials.This is why we continue to monitor the safety of medicines on the market, Ward added.A major study published in the journal Nature Medicine in January 2025 set out to systematically analyse all the reported health risks of over 215,000 people taking GLP-1 drugs to treat diabetes.The researchers found risks of taking GLP-1 drugs beyond those previously recognized in clinical trials, including an 11 percent increased risk in arthritis and a 146 percent increased risk of pancreatitis
To overcome the very short half-life of GLP-1, DPP-IV inhibitors have been developed
These studies show that people with higher levels of vitamin D have a lower risk of disease, although they do not definitively prove that lack of vitamin D causes disease or that vitamin D supplements would lower risk
She says her fridge is full of boxes of Ozempic, Wegovy and Zepbound
Are there any safety concerns mixing GLP-1 with cholesterol medications
Combination with other agents might allow dose reduction of the GLP-1 component
