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Hold the skin firmly and create a V-shape with your thumb and forefinger to ensure proper administration

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Lamos EM, Malek R, Davis SN

A possible clue to their mechanism is provided by a trial with flumazenil (Anexate, Romazicon) a benzodiazepine receptor antagonist, published by Lader and Morton (Journal of Psychopharmacology 1992, 6, 357-63)

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