[8] In a GHRH-knockout mouse model animals that cannot make their own GHRH and therefore grow abnormally once-daily CJC-1295 normalized growth and body composition, while less frequent dosing was less effective
Treatment typically begins at 0.25 mg for four weeks before increasing in steps to 0.5 mg, 1.0 mg, 1.7 mg, and eventually 2.4 mg
Nausea, constipation, and fatigue are common side effects that can often be mitigated with hydration, dietary modifications, and regular dialogue with care providers
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Rapid weight loss from any causediet, bariatric surgery, or GLP-1 therapyincreases risk proportionally