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A Korean man who was working for the Americans learned of Millards interest in cleft surgery and brought him to see his 7-year-old son, who had a wide unrepaired unilateral cleft lip

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What they found: Mean weight loss: 2.6 kg vs 2.3 kg placebo , a difference of only 0.3 kg (1 %) Statistically non-significant Clinically unsatisfactory for the obesity indication Safety profile remained favorable Why it matters: The study stopped the development of AOD-9604 as a drug

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Constant blood sugar spikes and crashes drive weight gain by triggering intense hunger and forcing rapid fat storage