Ozempic and other glucagon-like peptide-1 (GPL-1) agonist medications accounted for 10% of the state employee health plans annual prescription drug spending, according to a North Carolina State Health Plan fact sheet
It is unclear in this study whether the benefits are independent from the impact on Type 2 diabetes a risk factor for dementia or whether the benefits are secondary to improving Type 2 diabetes. Dr
A key secondary endpoint was the amount of weight lost
This hormone is responsible for regulating blood sugar, insulin secretion, and appetite
Common step therapy requirements include trying metformin first (if type 2 diabetes is present), trialing a GLP-1 single-agonist like semaglutide (Ozempic or Wegovy) before moving to the dual-agonist tirzepatide, and documenting inadequate response or intolerable side effects on the prior medication
Who should look elsewhere Patients with insurance coverage for branded Wegovy or Zepbound