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The work broadened the therapeutic index beyond glucose control and opened the door to co-agonists

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[1] The Rome IV Diagnostic Criteria (a system developed to classify the functional gastrointestinal disorders) for chronic constipation, states that these symptoms must be present for six months or greater, and must accompany at least 25 percent of bowel movements in the last three months

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Journal of pediatric hematology/oncology

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