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Tirzepatide is administered subcutaneously once weekly and works by activating GIP and GLP-1 receptors to enhance glucose-dependent insulin secretion, suppress glucagon release, slow gastric emptying, and reduce appetite

doi: 10.1016/j.cardfail.2020.04.005 47 MatsuuraTRPuchalskaPCrawfordPAKellyDP

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In addition, SOD was measured using specific colorimetric assay kits (Arbor Assays Company, 1514 Eisenhower Place Ann Arbor, Michigan 48108 USA, Catalog Number K028-H1), while GPx was measured using particular colorimetric assay kits (BioAssay Systems Company, Hayward, CA 94545, USA, Catalog Number: EGPX-100) following the manufacturers instructions for each test