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These findings point to a potential increased transport to and/or production of acylcarnitines within the brain of E4 mice following challenge

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Some research does point out the possibilities of oxalate nephropathy, hypernatremia, glucometer error, and other negative effects, but these studies are fairly small, havent been reproduced, and do not prove that IV high-dose vitamin C therapy is more harmful than placebo in double-blind randomized controlled trials