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Several trials are currently underway to investigate these effects further, as well as studies in humans that focus on the acute effects these drugs have on cardiac and vascular function, kidney physiology, and neurohormonal pathways
Curr Neuropharmacol (2020) 18(11):110625
Controversies concerning vitamin K and the newborn
Head-to-Head Superiority (SURMOUNT-5): The SURMOUNT-5 trial, with detailed results published in The New England Journal of Medicine on May 11, 2025, directly compared Tirzepatide (Zepbound) with semaglutide (Wegovy)