These metabolic potential treatments include triheptanoin, ketogenic diet, caprylic triglyceride, dichloroacetate, the Deanna protocol, pyruvate, lactate, creatine, coenzyme Q10, MitoQ, dexpramipexole, acetyl-L-carnitine and olesoxime, which we will discuss below
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Studies have suggested that other ion channels, such as histamine-gated chloride channels, pH-gated chloride channels, nicotinic acetylcholine receptors (nAChRs), and gamma amino butyric acid (GABA)-gated chloride channels are also targeted, but this may be a downstream effect as a result of glutamate-gated chloride (GluCl) channel inhibition (Fuse et al