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Not only is the fetal BBB immature during early brain development, but BBB function is disrupted in fetal and neonatal offspring of obese mothers, meaning there could be increased fetal hypothalamic exposure to GLP1RAs in the population of women who would be taking GLP1RAs during the perinatal period

Adv Clin Chem 74:103141 Huang A et al (2015) Exosomal transfer of vasorin expressed in hepatocellular carcinoma cells promotes migration of human umbilical vein endothelial cells