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Semaglutide dosing protocol The standard semaglutide titration for weight management follows a well-established 16-20 week escalation schedule: Weeks 1-4: 0.25 mg once weekly Weeks 5-8: 0.50 mg once weekly Weeks 9-12: 1.0 mg once weekly Weeks 13-16: 1.7 mg once weekly Week 17 onward: 2.4 mg once weekly (maintenance dose) This graduated approach serves two purposes

Focus on lean proteins, vegetables, whole grains, and healthy fats

Higher concentration means fewer units per dose, smaller injection volumes, and the vial lasts longer in terms of liquid

Clinical studies showed similar half-lives across younger and older adults

Many people fear that the weight they worked so hard to lose will quickly return

This is exactly why the reconstitution chart matters so much for split dosing