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Expanded reimbursement increases the number of eligible patients, requiring pharmaceutical companies to adjust marketing, physician education, payer engagement, and commercial planning strategies

Loprinzi et al., 2018)

4 Discussion Compared with RG group, more reductions of Scr, BUN, UA, and better improvement of eGFR were observed in RG + CHF group

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More emphasis needs to be put on supporting those who actually are running trials trying to figure out this information or forcing large phase 3 trials (who are collecting this data) to actually report on the outcomes, so we can provide evidence based DIET & EXERCISE recommendations