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That does not establish a universal clinical outcome for every human patient

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B12 deficiencies can lead to skin hyperpigmentation, vitiligo, changes to your hair, nail discolouration, and angular stomatitis (where the corners of your mouth become red and cracked)

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44,45 In a meta-analysis of 48 RCTs including 27,729 participants, the overall incidence of GI adverse events was reported to be 11.6%, with nausea identified as the most common symptom (21.4%)

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