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Central prolactin infusion in rats increases food intake, but prolactin receptor knockout mice show reduced adiposity and prolactin deficiency had only negligible effects on body weight, body composition, serum lipids and adiponectin concentrations (63, 64)

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The intestinal epithelial layer plays an essential role in separating luminal components, including microbes and dietary components, from systemic circulation to limit their interaction with the subepithelial immune system (Luissint et al

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