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At that time, attempts to extract safety signals from user-generated online content were constrained by the difficulty of mapping informal descriptions of symptoms to standardised clinical vocabularies such as the Medical Dictionary for Regulatory Activities

reported that ZIKV induces ROS production and suppresses the activities of antioxidant enzymes, including SOD and catalase, in U87-MG (human glioblastoma) and HepG2 (human liver carcinoma) cell lines 50

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