Insulin may be required when other treatments are insufficient, during severe illness or where insulin deficiency is marked
Always avoid injecting into areas that are bruised, red, or swollen
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When you eat, blood sugar rises, insulin rises, and the GH response to CJC-1295/Ipamorelin is severely blunted
This natural decline is one of the core reasons skin appears thinner over time, but peptides like GHK-Cu have been shown to help stimulate new collagen production
Options include: Other GLP-1 receptor agonists (such as semaglutide or dulaglutide), though these share similar mechanisms and side effect profiles SGLT2 inhibitors (such as dapagliflozin or empagliflozin), which work through different mechanisms and have cardiovascular and renal benefits DPP-4 inhibitors (such as sitagliptin), which have a more modest effect on glycaemic control and weight Metformin (if not already prescribed), which remains the first-line treatment for type 2 diabetes according to NICE guidelines Insulin therapy (for patients requiring more intensive glycaemic control) For weight management specifically , alternatives to tirzepatide (Zepbound) include semaglutide 2.4 mg (Wegovy), which is approved by NICE for managing overweight and obesity, orlistat, or comprehensive lifestyle intervention programmes