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FDA-approved obesity medications (OMs) are safe, evidence-based therapies that target specific physiology to improve the disease and are most effective when used as part of a comprehensive treatment plan

PMID 28678785

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J Biol Chem 291(44):2286122867 Zhang C, Liu J, Zhao Y et al (2016b) Glutaminase 2 is a novel negative regulator of small GTPase Rac1 and mediates p53 function in suppressing metastasis

In addition, ferroptosis associated with mitochondrial morphological changes, such as smaller size and increased membrane density, was implicated in PET NPs-induced lung injury