You may not get enough B12 in your diet if you are: Vegan Vegetarian Over 50 Living with digestive conditions that affect nutrient absorption, such as IBS, celiac, or Crohns disease Taking certain medications like metformin or proton pump inhibitors (PPIs) What are the symptoms of B12 deficiency
Having an autoimmune disease : Some autoimmune diseases can damage the stomach lining (including pernicious anemia) where intrinsic factor is produced
Doctors need to know these differences to provide the best care
Mechanisms of Action B-complex vitamins serve as coenzymes or precursors in numerous biochemical reactions, and together they work synergistically to support metabolism, neurological function, and cellular energy production
Researchers are interested in the enzyme because it connects nicotinamide metabolism, NAD-related pathways and the cellular methyl-donor system
However, it has been shown that high blood levels of vitamin B12 can cause the diagnostic features of cobalamin deficiency , which is due to binding to the different transport proteins