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A STAT binding site that stimulates POMC transcription and which partly overlaps with the Nur response element has been identified within the POMC promoter (37)

doi: 10.1073/pnas.91.4.1219 97 PalmiterR

Nat Metab 6:273289 Lytrivi M, Castell A-L, Poitout V, Cnop M (2020) Recent insights into mechanisms of -Cell Lipo- and glucolipotoxicity in Type 2 diabetes

Its also found within amyloid plaques, where it may act as a TREM2 ligand

Often referred to as the "master antioxidant," glutathione helps neutralize free radicals, support detoxification pathways, and maintain healthy cellular function

Xu B, Wang Y, Zhang S, Guo Q, Jin Y, Chen J, Gao Y, Ma H (2017) Transcriptomic and physiological analyses of Medicago sativa L