In the UK, the Medicines and Healthcare products Regulatory Agency (MHRA) launched a review in July 2023 into the risk of suicidal thoughts and thoughts of self-harm associated with GLP-1 RAs, including exenatide, liraglutide, lixisenatide, dulaglutide and semaglutide
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It can affect the heart, blood vessels, gastrointestinal organs, lungs and other respiratory organs, kidneys, skin, eyes, and nervous system, and it can lead to shock, impaired organ function, and even organ failure
doi: 10.3389/fimmu.2017.01468 141 GaspaniLLimiroliEFerrarioPBianchiM
Saxagliptin may also cause urinary tract infections and peripheral edema (3.6% and 6.8%, respectively)
Essa combinao potencializa significativamente a ao regeneradora do peptdeo
