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Characterization of human cytochrome P450 mediated bioactivation of amodiaquine and its major metabolite N-desethylamodiaquine

On admission to the hospital, she had abdominal pain and a sore throat with a normal serum copper level

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This protective effect is further supported by observations that GPX4 levels are diminished in cardiomyocytes of patients with diabetic heart disease [219], suggesting therapies of ferroptosis antioxidants have shown promise in alleviating diabetes-induced oxidative stress and cardiac dysfunction