Additionally, rare deficiencies of glutathione cycle enzymes (gamma-glutamylcysteine ligase, glutathione synthetase, 5-oxoprolinase, and gamma-glutamyl transferase) have all been associated with neuropsychiatric and cognitive impairments, although detailed phenomenological characterization has not been reported
These side effects are generally dose-manageable and often resolve with dose adjustment or time
Lawton, L
Adipose tissue in Walker 256 tumour-induced cachexia:possible association between decreased leptin concentration and mononuclear cell infiltration
Some tolerate the drugs, but others experience nausea and vomiting so unpleasant that they stop taking them
Low levels are associated with aging, increased risk of infections (including COVID-19), cancer, neurological problems, diabetes, and more