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Many patients who prepare this way experience minimal reflux

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The solution should appear clear and colorless, without any particles

Every puncture introduces a small risk of contamination, and 28 days represents a conservative but scientifically supported window for multi-dose use

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BMJ 379:e071380 Altintas Dogan AD, Hilberg O, Hess S, Jensen TT, Bladbjerg EM, Juhl CB (2022) Respiratory effects of treatment with a Glucagon-Like Peptide-1 receptor agonist in patients suffering from obesity and chronic obstructive pulmonary disease