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In amphetamine-induced stereotypy models (a pre-clinical model of schizophrenia-like conditions), DSIP normalised brain metabolism and MAO activity disrupted by long-term amphetamine treatment, establishing a role for adrenergic system normalisation as a mechanism of DSIPs neuroprotective activity
PMID: 28722967
However, it can develop in new areas with sufficient triggers
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Multiply that loss across a multi-week protocol, and you are looking at hundreds of dollars dissolving into degraded, inactive fragments
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