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Cancer cells undergo metabolic reprogramming to sustain cell viability and growth in hypoxic and nutrient-deficient environments

Recent studies have revealed that dysregulation of mitochondrial dynamicsincluding impaired mitophagy, imbalances in mitochondrial fusion and fission, and defects in mitochondrial biogenesisis closely associated with CRC initiation, progression, and resistance to therapy [46]

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Verkhratsky, A., Zorec, R

while the clone of recombinant protein L comes from Magnus peptidostreptococcus Both G and A protein specifically bind to IgG's Fc region, whereas protein IgG's kappa light chains are bound by L