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Typical titration schedule (for Wegovy, for example): Week 14: 0.25 mg once weekly Week 58: 0.5 mg once weekly Week 912: 1.0 mg once weekly and so on, up to the full dose (e.g., 2.4 mg for Wegovy) Each step usually lasts at least 4 weeks to give your body time to adapt

How long it lasts depends entirely on your weekly dose

According to a systematic review and meta-analysis published in Cureus , tirzepatide produced significantly greater weight loss than semaglutide across multiple studies, with benefits increasing at higher doses and longer treatment durations

Ozempic lowers fasting and postprandial blood glucose by stimulating insulin secretion in a glucose-dependent manner

Total doses depend on your weekly dose

Kidney damage : Reports have suggested that Ozempic may contribute to kidney problems, particularly in individuals with pre-existing conditions