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Improved long-term outcome with chemoradiotherapy strategies in esophageal cancer

Mechanistically, glutathione peroxidase 4 and ferrous iron, which are pivotal ferroptosis regulators, were upregulated in residual cells or tumors, and were hence potential therapeutic targets of persister cells

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Bei einem strkeren Mangel des Enzyms, welches das krpereigene Glutathion herstellt, (Glutathion-Synthetase) knnen sogar Fehlfunktionen des Nervensystems, wiederkehrende bakterielle Infektionen, sowie Verlangsamung von krperlichen Reaktionen, Bewegungen und Sprache auftreten

However, in some situations, this reduction process fails, resulting in the release of the highly reactive O 2

10.1523/JNEUROSCI.3903-07.2007 J