The study titled, "A Genetic Risk Score Associated with Nausea Resulting from GLP-1 Agonist Treatment: A Post-Hoc Analysis of a Randomized Controlled Trial of Liraglutide," analyzed post-hoc genetic data from 110 participants
What Happens to Muscle on GLP-1s Like Ozempic GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound, Mounjaro) work by mimicking a natural hormone that slows gastric emptying, reduces appetite, and improves satiety
Klein C, Dutrow B, Philpotts A
With their increasing use, it is important to understand what a GLP-1 agonist is and does while also understanding that being on a GLP-1 agonist drives up the necessity of some things relative to ones health
Bagshaw and Wald, 2021)
While the precise mechanism of action for weight management is not fully understood, tirzepatide appears to work through multiple pathways that contribute to weight reduction