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Yes, and you need to understand the reason behind this: In nondiabetic obesity trials , weight loss tends to be larger (especially with tirzepatide or high-dose semaglutide)

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Those cells then die off gradually through a process called apoptosis and are naturally cleared by the body over the following weeks and months

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Nausea, reduced food intake, and rapid body change can change energy and sleep, and these shifts can look like mood swings or anxiety