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Risk of bias assessment was performed using the Cochrane Risk-of-Bias tool for randomized trials
In practice, clinicians commonly begin with 0.5 g - 2 g (10 - 40 mL of 50 mg/mL solution) administered as a slow IV push or diluted infusion, adjusting per response
Light irradiation can induce an increase in XO activity in epidermal keratinocytes and endothelial cells and produce more oxygen free radicals (38)
Summary Keywords topiramate, migraine, oxidative stress, neurogenic inflammation, ferroptosis Citation Chen Q-W, Meng R-T and Ko C-Y (2024) Modulating oxidative stress and neurogenic inflammation: the role of topiramate in migraine treatment
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