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Nausea is the most common, with relative risk ratios of 2.69 at 4 mg, 4.27 at 8 mg, and 4.00 at 12 mg compared to placebo

Additionally, the lack of imbalance in the PASADENA trial in the proportion of events reached prior to starting symptomatic therapy between treatment groups (97% in placebo-treated group and 96% in the prasinezumab-treated group) could potentially influence the relative robustness of the TTE and MMRM approaches in future trials