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The continuation group kept losing, net negative 17.4 percent from baseline

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As an alternative strategy to target IGF signaling, results of phase 1 clinical trials of the dual IGF1/2-neutralizing antibodies have been reported, while no results of phase 2/3 trials in cancer therapy have been reported [156, 157]

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While it is still not FDA-approved, it is being clinically tested and studied as a solution for obesity

Interferon Regulatory Factor 4 (IRF4) promotes lipopolysaccharide-induced colonic mucosal epithelial cell proliferation by regulating macrophage polarization