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Tesofensine is a triple monoamine reuptake inhibitor that works through the central nervous system by increasing levels of dopamine, norepinephrine, and serotonin

SLU-PP-332 has the strongest preclinical exercise-mimetic signature of the three, but zero human clinical data

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However, most germlines of div-1(or148ts) mutants grown at 25C had no or less stem cell-like state (state(I)) (72%, n=42) (Fig