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Currently, there are over hundreds of lawsuits that have been centralized in multidistrict litigation against the manufacturers of GLP-1 receptor agonists

10.1067/mlc.2000.105977 68

Kitzman DW, Brubaker P, Morgan T et al (2016) Effect of caloric restriction or aerobic exercise training on peak oxygen consumption and quality of life in obese older patients with heart failure with preserved ejection fraction: a randomized clinical trial

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In preclinical models, it has demonstrated pro-angiogenic, cytoprotective, and anti-inflammatory properties 1-3

This PWA model mimics a subtype of PCOS patients that exhibit chronic hyperandrogenism, with marked metabolic, hormonal, and reproductive/gonadal alterations, which represent the majority of cases