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doi: 10.1016/j.prp.2020.153314 23 ZhangYMengQSunQXuZXZhouHWangY

Glutamine blockage by JHU083 downregulated glycolysis and oxidative phosphorylation in cancer cells, resulting in a concomitant decline in hypoxia, acidosis, and nutrient depletion while enhancing anticancer immunity and oxidative phosphorylation in T-cells

In a later study, Biswas et al

In the second step, glutathione synthetase (GS) adds glycine to glutamyl-cysteine to form glutathione (-glutamyl-cysteinyl-glycine)

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