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In other words, it is not a synthetic invention so much as a naturally occurring signaling molecule that researchers have tried to understand and, in places, to study therapeutically

Oxidative and endoplasmic reticulum stress responses to chronic high-altitude exposure during the development of high-altitude pulmonary hypertension

Qiao H, Ren H, Du H, Zhang M, Xiong X, Lv R

[13] As crackles are not specific for IPF, they must prompt a thorough diagnostic process

Crit Rev Toxicol 21:2150 Khalili MR, Sadati MS, Jahanbani-Ardakani H (2021) Outbreak of methanol-induced optic neuropathy amid COVID-19 pandemic

They were covered for diabetes and, now will be covered for obesity