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Immunofluorescence analysis showed that GSH treatment caused glomerular-like structures to be organized in a pattern similar to that in WT kidney organoids, while the glomerular-like structures were linear and unorganized in Fabry kidney organoids (Fig

Chronic cerebral hypoperfusion induces microglial activation, polarized toward M1 (pro-inflammatory) phenotype, and the drug fingolimod has been shown, in an animal model, to attenuate such microglia-mediated neuroinflammation and to promote oligodendrocytogenesis by shifting microglia toward M2 subtype (217)

Familial-inherited epilepsy has also been associated with mutations in KCNQ2 and KCNQ3 [185,186,187]

[3] Patients with deficiencies often experience fatigue, cognitive or nerve impairments, and slow recovery

Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer