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Altered B12 handling and reduced clearance in kidney disease, and both cellular release and reduced clearance in liver disease, can raise B12, so supportive renal or hepatic findings make those causes plausible

This process can temporarily lower potassium reserves, as more potassium gets pulled into cells to support new tissue growth and energy production

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Thus, researchers have investigated the use of growth factors to increase cell recruitment, improve cell chondrogenesis, and optimize chondrocyte populations for cartilage regeneration therapies

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