The best course of treatment for melasma would be sun avoidance, using a mineral-based sunscreen combined with topical skincare products with hydroquinone, Retinoids, Vitamin C, Kojic Acid, Niacinamide, Alpha Hydroxy Acids, Beta Hydroxy Acids, Azelaic Acid, and Arbutin
doi:10.1056/NEJMoa2206038 Campbell P
Consistent with the distribution of Firmicutes in the cecal samples, the relative abundance of Ileibacterium was highest in the WD controls (average relative abundance 68%), second highest in the LD controls (average relative abundance 51%), and lowest in the vehicle- and 5A-1MQ-treated mice switched from WD to LD (average relative abundances of 40% and 41%, respectively)
Related Reading --- Disclaimer: GHK-Cu is not FDA-approved
Alcohol swabs for skin preparation
Glutathione Injection for Skin Lightening and Rejuvenation Multiple studies have confirmed that glutathione injections help lighten the skin by converting melanin to a lighter color and improving uneven skin tone