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The potential of SLU-PP-332 as a "exercise mimetic" to increase energy expenditure and fat oxidation is unmatched, even if its mode of action differs from that of 5-amino-1MQ, which operates via NNMT inhibition and ERR activation, respectively

Additionally, GLP-1R agonists inhibit tau protein hyperphosphorylation, promote the release of brain-derived neurotrophic factor, and reduce neuroinflammatory responses by inhibiting microglial and astrocyte activation [55,56,57]

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However, the results of this studyindicate that the alterations caused by riboflavin deficiency lie not only at the enzymatic activity level, but also at the protein expression level for the flavin-containing enzymes

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