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doi: 10.1016/j.neurobiolaging.2017.10.002 38 HampelHMesulamMMCuelloACFarlowMRGiacobiniEGrossbergGTet al

Similar to WASP, loss of WAVE protein or manipulations of its phosphorylation status by cyclin-dependent kinase 5 (Cdk5) also caused deficits in spine formation and maintenance in mice (Soderling et al., 2003, 2007

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The glucose-sparing effects of increased fat oxidation further protect lean tissue from catabolism during energy deficit states

"Public health and safety concerns have emerged around the complexity and commercial scale of some compounding of extemporaneously prepared GLP-1 RAs, which are sterile medicines containing high-risk active substances," the TGA said in a statement