Given that M-cells have well-accepted BT capability and overlie intestinal lymphoid aggregates, M-cell mediated BT is one plausible mechanistic explanation [16, 17]
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the phosphorylation of choline is catalyzed by the enzyme choline kinase
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Data analysis We used the Cochrane system for systematic Review (RevMan, version 5.4.1, Oxford, United Kingdom for data analysis, all the data were continuous, and the random effect was used due to the significant heterogeneity