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Aside from hyperhomocysteinemia, C677T or A1298C MTHFR (the two genes most studied) mutations are associated with an increased risk of other conditions including cardiovascular and thromboembolic diseases such as strokes, blood clots, and heart attacks, ADHD in children, pregnancies with neural tube defects, depression, anxiety, diabetic neuropathy, glaucoma migraines, schizophrenia, and colorectal polyps

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Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans

Patrick is also an associate scientist at the Fatty Acid Research Institute, where she is involved in projects investigating the role of omega-3 fatty acids in brain aging.

1956;11 doi: 10.1093/geronj/11.3.298