(2017) in Cell demonstrated that FOXO4-DRI selectively induced apoptosis in senescent cells in vitro and in vivo
identify SLC25A45 as a key metabolic switch and bottleneck that couples mitochondrial TML import to regulated carnitine biosynthesis during environmental adaptation
Carnitine has a metal chelating activity, similar to the medications used to remove poisonous metals from the body in cases of toxicity
Ghrelin, a gastrointestinal hormone, regulates energy balance and lipid metabolism
I., Cuzic S., Brajsa K., Mildner B., Bokulic A., Situm K., et al
IV glutathione provides immediate systemic delivery but introduces additional risks and lacks evidence as a routine anti-aging or detoxification treatment