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N Engl J Med (2011) 364(20):192031

Hydroxocobalamin and cyanocobalamin are both forms of Vitamin B12, but hydroxocobalamin stays in the body longer

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When glutamate release exceeds glutamate uptake, the excess glutamate activates a large number of postsynaptic NMDA-Rs, resulting in the induction of excitotoxic neuronal death by allowing excessive Ca 2+ influx through the receptor-operated cation channels [73]

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