Given that this condition predominantly affects children, dedicated pediatric registries and long-term studies are essential to address the paucity of data on developmental safety, effects on linear growth and pubertal progression, and long-term cardiometabolic outcomes
Based on some recent media reports, it seems peptides such as retatrutide may affect more than just appetite
Stress Management: Techniques like meditation, deep breathing, or yoga can reduce stress and support healthier choices
Ultimately, tissues are more vulnerable to OS and, consequently, to diabetic complications, especially vascular problems, which are the main cause of comorbidity and mortality in DM2
Muscle is one of the key regulators of metabolism, so losing it during weight loss can significantly impact long term health outcomes
The authors are grateful to all the participants in this trial, as well as the site investigators and staff