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Oral hyperpigmentation in HIV-infected patients

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Th17 cells mainly secrete the pro-inflammatory cytokines IL-17A, IL-17F, IL-21, and IL-22, while Treg cells inhibit autoimmunity and secrete IL-10 [50]

However, intravenous delivery does not allow for cell homing and in situ differentiation into tissue-specific functional cells because engraftment is often uncontrollable and mostly depends on chemotaxis toward a bioactive gradient

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